2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine

2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine - Names and Identifiers

Name	2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
Synonyms	LogP 2-CHLORO-6,7-DIHYDRO-5H-[1]PYRINDINE 2-chloro-5H,6H,7H-cyclopenta[b]pyridine 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 5H-Cyclopenta[b]pyridine, 2-chloro-6,7-dihydro- 5H-cyclopenta[b]pyridine, 2-chloro-6,7-dihydro- 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine, Fandachem
CAS	117890-55-8
InChI	InChI=1/C8H8ClN/c9-8-5-4-6-2-1-3-7(6)10-8/h4-5H,1-3H2

2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine - Physico-chemical Properties

Molecular Formula	C8H8ClN
Molar Mass	153.61
Density	1.241±0.06 g/cm3(Predicted)
Boling Point	236.5±40.0 °C(Predicted)
Flash Point	119.643°C
Vapor Presure	0.072mmHg at 25°C
pKa	1.39±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.584

2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine - Introduction

2-Chloro-6, 7-dihydro-5H-cyclopenta [B] pyridine, also known as hexahydroisonitrophenyl chloride, has the chemical formula C9H10ClN. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-chloro-6, 7-dihydro-5H-cyclopenta [B] pyridine is a colorless or slightly yellow crystalline powder.
-Melting point: about 60-62 ℃.
-Solubility: Soluble in organic solvents such as ethanol, dimethyl ether and chloroform, slightly soluble in water.

Use:
-2-Chloro-6, 7-dihydro-5H-cyclopenta [B] pyridine is commonly used as a reagent in organic synthesis and can be used to synthesize compounds with various biological activities.
-It has a wide range of applications in the field of medicine, and can be used as a drug intermediate or a raw material in a drug formula.

Preparation Method:
-2-chloro-6, 7-dihydro-5H-cyclopentyl [B] pyridine can be prepared by reacting hexahydroisobenzene with nitrous acid to generate 7-nitro-5H-cyclopentyl [B] pyridine, and then reacting with cuprous chloride to obtain the target product.

Safety Information:
-2-Chloro-6, 7-dihydro-5H-cyclopentyl [B] pyridine is relatively stable under general operating conditions, but it still needs to be used in accordance with laboratory safety procedures.
-During use, care should be taken to avoid contact with skin, eyes and substances taken or inhaled.
-If exposed to this compound, rinse the affected area immediately with plenty of water.
-Waste and residues need to be disposed of in accordance with local regulations.

Last Update：2024-04-09 02:00:41